Agent Name

Picramic acid

Alternative Name

4,6-Dinitro-2-aminophenol

CAS Number

96-91-3

Formula

C6-H5-N3-O5

Major Category

Nitrogen Compounds

Synonyms

4,6-Dinitro-2-aminophenol; 1-Amino-2-hydroxy-3,5-dinitrobenzene; 2,4-Dinitro-6-aminophenol; 2-Amino-4,6-dinitrophenol; CI 76540; 6-Amino-2,4-dinitrophenol; Acide picramique [French]; C.I. Oxidation Base 21; CI Oxidation Base 21; Fourrine 4R; Fourrine 93; Furro 4R; Oxidation Base 21; Phenol, 2-amino-4,6-dinitro-; Zoba 4R; [ChemIDplus] UN3317

Category

Other Aromatics (Nitrogen)

Description

Dark red solid; [Merck Index]

Sources/Uses

Used as an explosive initiator, an oxidation base for dyeing fur, a component of electric detonation fuses, a reagent for albumin, an acid-base indicator, and in rinses for hair dyes and shampoos; Also used to make mordants and azo dyes; [HSDB]

Comments

Subcutaneous LDLo (rat) = 2100 mg/kg; [RTECS] Toxicity similar to that of 2,4-dinitrophenol; [Merck Index] Emergency treatment: "Dinitro phenol group"; [HSDB] Highly flammable and explosive; Desensitized by wetting; An irritant; Symptoms of poisoning include dizziness, abdominal cramps, vomiting, bloody diarrhea, weakness, and convulsions; [CAMEO] See "Dinitrophenol."

Exposure Assessment
Vapor Pressure

4.16e-07 mm Hg

Explanatory Notes

Flash point = 210 deg C; [HSDB] The Guide in the Emergency Response Guidebook is for "2-Amino-4,6-Dinitrophenol, wetted with not less than 20% water."

Adverse Effects
Nephrotoxin

Yes

Hepatotoxin

Hepatotoxin, Secondary

Methemoglobinemia

Methemoglobinemia, Secondary

Anemia

Anemia, Hemolytic

Other Poison

Uncoupler

Dermatotoxin

Skin Burns

Links to Other NLM Databases
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Toxicity Information

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