Agent Name

Carbonyl sulfide

CAS Number

463-58-1

Formula

C-O-S

Major Category

Toxic Gases & Vapors

Synonyms

Carbon monoxide monosulfide; Carbon oxide sulfide; Carbon oxysulfide; Oxycarbon sulfide; UN2204; [ChemIDplus]

Category

Other Toxic Gases & Vapors

Description

Colorless gas with a rotten egg odor; [CHEMINFO MSDS]

Sources/Uses

Used as a chemical intermediate; Workers may be exposed during petroleum refining, coal destructive distillation, or rayon production; [HSDB] Produced naturally in soil and compost; Other sources are tobacco smoke, burning fossil fuels, gassification, and making petrochemicals; Also used as a grain fumigant and to make drugs, flavors, fragrances, pesticides, and rayon; [ACGIH]

Comments

Liquified gas can cause frostbite; [NJ-HSFS] TLV Basis = CNS impairment; Carbonyl sulfide is less toxic than hydrogen sulfide in animal experiments; A slight methemoglobinemia occurs in animals exposed to > 151 ppm; Adverse effects are due mainly to hydrogen sulfide; [ACGIH] Decomposes to hydrogen sulfide in moist air or lungs; [CHEMINFO MSDS] See "Hydrogen sulfide."

Exposure Assessment
Skin Designation (ACGIH)

Insufficient data

TIH

Yes

TLV (ACGIH)

5 ppm

Vapor Pressure

9410 mm Hg

Lethal Concentration

LC50 (rat) = 1,070 ppm/4H

Flammability (NFPA)

4: Burns readily

Adverse Effects
Toxic Pneumonitis

Yes

Methemoglobinemia

Methemoglobinemia, Secondary

Anemia

Anemia, Hemolytic

Other Poison

Chemical Asphyxiant

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

Chemical Information

Search ChemIDplus

Biomedical References

Search PubMed

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure:

Activities

Activities with risk of exposure: