Agent Name

Arsenic trichloride

CAS Number

7784-34-1

Formula

As-Cl3

Major Category

Metals

Synonyms

Arsenic butter; Arsenic chloride; Arsenic(III) chloride; Arsenic(III) trichloride; Arsenious chloride; Arsenous chloride; Arsenous trichloride; Butter of arsenic; Caustic arsenic chloride; Caustic oil of arsenic;Chlorure arsenieux [French]; Chlorure d'arsenic [French]; Fuming liquid arsenic; Trichloroarsine; Trichlorure d'arsenic [French]; [ChemIDplus] UN1560

Category

Arsenic Compounds, Inorganic

Description

Clear, oily liquid; [HSDB] Colorless liquid with an unpleasant odor; [CHRIS]

Sources/Uses

Used as a chemical intermediate for pharmaceuticals, insecticides, and chemical warfare blister agents; Used in the ceramics industry; [HSDB]

Comments

Corrosive to skin, eyes, and respiratory tract; Heavy inhalation exposure may cause pulmonary edema; Repeated exposures may cause arsenic poisoning; Lethal dose by ingestion is 70-180 mg; [CHEMINFO MSDS] See "Arsenic and inorganic compounds" and the linked occupational diseases.

Exposure Assessment
BEI

Inorganic arsenic plus methylated metabolites in urine = 35 ug As/L; end of workweek;

TIH

Yes

TLV (ACGIH)

0.01 mg/m3, as As

PEL (OSHA)

0.01 mg/m3, as As

IDLH (NIOSH)

5 mg/m3, as As

Vapor Pressure

8.26e-11 mm Hg

Explanatory Notes

Boiling point = 130.5 deg C; [ACGIH] For occupational exposure limits, see "Arsenic and compounds."

Adverse Effects
Reproductive Toxin

Yes

Skin Sensitizer

Yes

Toxic Pneumonitis

Yes

Neurotoxin

Sensorimotor Neuropathy

Hepatotoxin

Hepatotoxin, Secondary

Anemia

Anemia, Aplastic

Dermatotoxin

Skin Burns

IARC Carcinogen

Known Carcinogen

NTP Carcinogen

Human Carcinogen

ACGIH Carcinogen

Confirmed Human

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

Chemical Information

Search ChemIDplus

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: