Agent Name

Arsenic acid

CAS Number

7778-39-4

Formula

As-H3-O4

Major Category

Metals

Synonyms

Acide arsenique liquide [French]; Arsenate; Arsenic acid (H3AsO4); Arsenic acid, liquid; Crab grass killer; Desiccant L-10; Dessicant L-10; HI-Yield desiccant H-10; Orthoarsenic acid; Scorch; Zotox; Zotox Crab Grass Killer; [ChemIDplus] UN1553(liquid); UN1554(solid);

Category

Arsenic Compounds, Inorganic

Description

White solid; Commercial grade (75%) is a very pale yellow liquid; [HSDB] Hemihydrate is hygroscopic; [Merck Index] Pale yellow liquid with a light sweet odor; [MSDSonline]

Sources/Uses

Used to make arsenates and glass; Also used as a wood preservative, defoliant, desiccant for cotton, and soil sterilant; [Hawley]

Comments

Chemical formula is H3AsO4.1/2H2O; [Hawley] Exists only as hemihydrate; [Merck Index] Toxic by inhalation, ingestion, and skin absorption; [CAMEO] Arsenic acid (80% in water) can cause arsenic poisoning; [ICSC] A corrosive substance that can cause injury to the skin, eyes, and respiratory tract; [MSDSonline] See "Arsenic and inorganic compounds" and the linked occupational diseases.

Exposure Assessment
BEI

Inorganic arsenic plus methylated metabolites in urine = 35 ug As/L; end of workweek;

TLV (ACGIH)

0.01 mg/m3, as As

PEL (OSHA)

0.01 mg/m3, as As

IDLH (NIOSH)

5 mg/m3, as As

Explanatory Notes

The TLV is for "Arsenic acid and its salts, as As; [ACGIH] The Guide in the Emergency Response Guidebook is for "Arsenic acid, liquid."

Adverse Effects
Reproductive Toxin

Yes

Neurotoxin

Sensorimotor Neuropathy

Hepatotoxin

Hepatotoxin, Secondary

Anemia

Anemia, Aplastic

IARC Carcinogen

Known Carcinogen

NTP Carcinogen

Human Carcinogen

ACGIH Carcinogen

Confirmed Human

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

Chemical Information

Search ChemIDplus

Biomedical References

Search PubMed

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: