Agent Name

Naled

Alternative Name

Dibrom

CAS Number

300-76-5

Formula

C4-H7-Br2-Cl2-O4-P

Major Category

Pesticides

Synonyms

1,2-Dibromo-2,2-dichloroethyl dimethyl phosphate; Alvora; Arthodibrom; BRP; Bromchlophos; Bromex; Bromex (insecticide); Bromex 50; Dibrom; Dibromfos; Dimethyl 1,2-dibromo-2,2-dichloroethyl phosphate; Ethanol, 1,2-dibromo-2,2-dichloro-, dimethyl phosphate; Flibol Ex; Fosbrom; Fosforan O-1,2-dwubromo-2,2-dwuchloroetylo-O,O-dwumetylowy [Polish]; Hibrom; Naledu [Polish]; Nikabrom; O,O-Dimethyl O-2,2-dichloro-1,2-dibromoethyl phosphate; O,O-Dimethyl-O-(1,2-dibrom-2,2-dichlor-aethyl)-phosphat [German]; O,O-Dimethyl-O-(1,2-dibromo-2,2-dichloroethyl)phosphate; O-(1,2-Dibrom-2,2-dichlor-aethyl)-O,O-dimethyl-phosphat [German]; O-(1,2-Dibromo-2,2-dicloro-etil)-O,O-dimetil-fosfato [Italian]; O-(1,2-Dibroom-2,2-dichloor-ethyl)-O,O-dimethyl-fosfaat [Dutch]; OMS 75; Ortho 4355; Ortho-dibrom; Orthodibromo; Phosphate de O,O-dimethyle et de O-(1,2-dibromo-2,2-dichlorethyle) [French]; Phosphoric acid, 1,2-dibromo-2,2-dichloroethyl dimethyl ester (8CI)(9CI); RE-4355; [ChemIDplus]

Category

Organophosphate Insecticides

Description

Colorless to white solid or straw-colored liquid (above 80 degrees F) with a slightly pungent odor. [insecticide]; [NIOSH]

Sources/Uses

Used to kill aphids, mites, mosquitoes, and flies; also used by veterinarians to treat worm infections in dogs; [EXTOXNET] Used as an insecticide and acaricide in field crops, greenhouses and mushroom cultivation; Also used to kill mosquitoes; [ACGIH]

Comments

Classified as "moderately toxic," naled has an LD50 of 91 to 430 mg/kg in rats; Skin sensitization has been reported; [EXTOXNET] Structurally similar to dichlorvos; A dermal sensitizer; [ACGIH]

Reference Link

EXTOXNET PIP - NALED

Exposure Assessment
BEI

Cholinesterase activity in red cells = 70% of individual's baseline, sample time discretionary; [ACGIH]

Skin Designation (ACGIH)

Yes

TLV (ACGIH)

0.1 mg/m3, inhalable fraction and vapor

MAK

1 mg/m3

Excerpts from Documentation for IDLHs

Basis for original (SCP) IDLH: Because no useful data on acute inhalation toxicity are available, the chosen IDLH has been estimated from the male rat oral LD50 of 250 mg/kg [Gaines 1969 cited by ACGIH 1971]. ACGIH [1971] also reported that the acute toxicity data, inhalation data, and experience to date indicate that this is not a highly dangerous material. . . . Human data: None relevant for use in determining the revised IDLH.

Vapor Pressure

0.0002 mm Hg

Lethal Concentration

LC (mice) > 1,500 mg/m3/6h

Reference Link

EPA Pesticide Fact Sheet: Naled - 2002

Adverse Effects
Skin Sensitizer

Yes

Other Poison

Organophosphate

ACGIH Carcinogen

Not Classifiable

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

Chemical Information

Search ChemIDplus

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: