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Sensitization to drugs occurs during production and use: 1. Handling by pharmaceutical chemists and technicians; 2. Packaging and cleaning by manufacturing workers; 3. Hand-compounding by pharmacists; 4. Mixing animal feeds by farmers; 5. Crushing tablets or preparing lyophilized solutions by nurses; 6. Applying topical drugs to patients by nurses or physical therapists; [Kanerva, p. 479] Allergic Reactions in Pharmacists and Pharmaceutical Workers OA = Occupational Asthma ACD = Allergic Contact Dermatitis CU = Contact Urticaria PACD = Photoallergic Contact Dermatitis ANTIBIOTICS Ampicillin OA Amoxicillin OA CU Azithromycin CU Bacitracin ACD Cephalosporins OA CU Chloramphenicol ACD Gentamycin ACD Iodochlorhydroxyquin (Vioform) ACD Isoniazid OA Lincomycin ACD Mezlocillin CU Neomycin ACD Nitrofurazone (Furacin) ACD Pencillin OA CU Piperacillin OA Spectinomycin ACD Spiramycin OA Streptomycin CU Sulbactam CU Sulfanilamide PACD Sulfathiazole OA Tetracyclines OA Thimerosal (Merthiolate) ACD Vancomycin OA Virginiamycin ACD CHEMOTHERAPEUTIC AGENTS Azathioprine (Imuran) ACD Cisplatin CU Mitoxantrone OA ANTIHYPERTENSIVES Methyldopa OA Hydralazine OA ACD Alprenolol ACD Labetalol ACD Oxprenolol ACD Propanolol ACD NSAIDS Benzydamine (Difflam) ACD PACD Piroxicam (Feldene) ACD OTHER AGENTS Albendazole CU Azoperone ACD Benzocaine ACD Cimetidine OA Chlorpromazine PACD Codeine OA ACD Disulfiram (Antabuse) ACD Donepezil CU Famotidine (Pepcid) ACD Ipecac OA Levomepromazine CU Methamizole CU Morphine OA ACD Penicillamine OA Promethazine PACD Propacemetol ACD Phenothiazine PACD Procaine hydrochloride ACD Psyllium OA Quinidine ACD Ranitidine OA ACD Salbutamol intermediate OA Tafenoquine OA Tetracaine ACD from [Marks] and [Malo]; CU based on [Kanerva]"^^^^^^^0^^^^0^1^0^1^1^0^0^0^0^^0^0^^^0^0^^0.00^0.00^0.00^0^0.00^0.00^^0.00^^^^^^1^^^"Drugs: Skin and Respiratory Allergens#

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