Agent Name

Cycloleucine

CAS Number

52-52-8

Formula

C6-H11-N-O2

Major Category

Nitrogen Compounds

Synonyms

1-Amino-cyclopentanecarboxylic acid; 1-Aminocyclopentane-1-carboxylic acid; ACPC; CB 1639; Cycloleucin; Cyclopentanecarboxylic acid, 1-amino-; WR 14,997; X 201; [ChemIDplus]

Category

Amino Carboxylic Acids

Description

Solid; [Merck Index] Crystalline powder; [Alfa Aesar MSDS]

Sources/Uses

A synthetic amino acid used in amino acid transport studies and in testing for immunosuppression in mice; [Merck Index] Used as experimental tumor screening agent; [HSDB]

Comments

Possesses cytostatic, immunosuppressive, and antineoplastic properties; [ChemIDplus] Evidence of neurotoxicity in experimental animals; [HSDB] Causes urine changes in 3-day intermittent intraperitoneal studies of rats; Causes muscle weakness and hemorrhage in 15-day intermittent intravenous studies of dogs; Oral administration in humans causes anorexia and nausea or vomiting; [RTECS] An irritant; Harmful by ingestion; [Alfa Aesar MSDS]

Exposure Assessment
Vapor Pressure

2.63E-9 mm Hg

Adverse Effects
Neurotoxin

Other CNS Neurotoxin

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Other Information

No other related information on this agent was found.