Agent Name

Bronopol

CAS Number

52-51-7

Formula

C3-H6-Br-N-O4

Major Category

Other Uses

Synonyms

2-Bromo-2-nitropropane-1,3-diol; 2-Nitro-2-bromo-1,3-propanediol; Bronidiol; Bronocot; Bronopol; Bronopolu [Polish]; Bronopolum [INN-Latin]; Bronosol; Bronotak; Lexgard bronopol; Onyxide 500; beta-Bromo-beta-nitrotrimethyleneglycol; [ChemIDplus] UN3241

Category

Biocides/Disinfectants

Sources/Uses

Bronopol is a preservative and antiseptic used in cosmetics and topical medications. It is used as a preservative in paints, textiles, cooling towers, humidifiers, and hide processing. [Marks, p. 136-7] Used in cleaning agents, paints, cosmetics, glues, paper mills, water systems, metalworking fluids, polishes, and printing inks; [Kanerva, p. 405]

Comments

Bronopol is a skin sensitizer. Cosmetic preparations contain concentrations of 0.01% to 0.02%. Significant irritant effects are seen when the concentration reaches 1% or greater. [Marks, p. 136-7] Skin sensitization reported in dairy workers and a veterinarian using a gel for ultrasound examinations; [Kanerva, p. 1762] A skin, eye, and respiratory tract irritant; A skin sensitizer; [ICSC]

Reference Link

Milk recorder dermatitis

Exposure Assessment
Vapor Pressure

126000 mm Hg

Reference Link

EPA Pesticide Fact Sheet: Bronopol - 1995

Adverse Effects
Skin Sensitizer

Yes

Links to Other NLM Databases
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