Agent Name

Propylene glycol n-butyl ether

Alternative Name

PGBE

CAS Number

5131-66-8

Formula

C7-H16-O2

Major Category

Solvents

Synonyms

Butoxypropanol; 1,2-Propylene glycol 1-monobutyl ether; 1-Butoxy-2-propanol; 2-Hydroxy-3-butoxypropane; Propasol solvent B; Propylene glycol monobutyl ether; n-Butoxy-2-propanol; n-Butoxypropanol; 1-Butoxypropan-2-ol; 2-Propanol, 1-butoxy-; [ChemIDplus] PnB; [Reference #1] Dowanol PNB glycol ether; [Dow Chemical MSDS] PGBE; [Glycol Ethers Online]

Category

Glycol Ethers (P Series)

Description

Colorless liquid; [ICSC] Odor of ether; [Dow Chemical MSDS]

Sources/Uses

Propylene series glycol ethers are used in surface coatings, leather, pesticides, electrical, industrial cleaners, resins, and printing inks; [ToxPlanet: ECETOC] Used as a coupling agent and solvent (degreasers, paint removers, metal cleaners, and hard surface cleaners), coalescent (latex coatings), coupling agent (water-based agricultural formulations), and chemical intermediate (epoxides, acid ester derivatives, solvents, and plasticizers); [Reference #1]

Comments

Adverse effects in animal studies include adaptive liver changes and reversible CNS depression, but no hematological, genotoxic, or carcinogenic effects; [ToxPlanet: ECETOC] A skin and eye irritant; [ICSC] May cause moderate skin and eye irritation; May cause mild, reversible corneal injury; [Dow Chemical MSDS] See "Dipropylene glycol n-butyl ether."

Reference Link

OECD SIDS: Propylene Glycol Ethers - 2003

Exposure Assessment
Vapor Pressure

1.4 mm Hg

Lethal Concentration

LC50 (rat) > 3,520 mg/m3/4hr

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

Links to Other NLM Databases
Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Biomedical References

Search PubMed

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: