Agent Name

m-Nitroaniline

CAS Number

99-09-2

Formula

C6-H6-N2-O2

Major Category

Nitrogen Compounds

Synonyms

1-Amino-3-nitrobenzene; 3-Aminonitrobenzene; 3-Nitroaniline; 3-Nitrobenzenamine; 3-Nitrophenylamine; Amarthol Fast Orange R Base; Aniline, m-nitro-; Azobase MNA; Benzenamine, 3-nitro-; C.I. 37030; C.I. Azoic Diazo Component 7; CI 37030; CI Azoic Diazo Component 7; Daito Orange Base R; Devol Orange R; Diazo Fast Orange R; Fast Orange Base R; Fast Orange M Base; Fast Orange MM Base; Fast Orange R Base; Fast Orange R Salt; Hiltonil Fast Orange R Base; MNA; Naphtoelan Orange R Base; Nitranilin; Orange Base Irga I; m-Aminonitrobenzene; m-Nitraniline; m-Nitroaminobenzene; m-Nitroaniline; m-Nitrophenylamine; [ChemIDplus] UN1661

Category

Nitroanilines

Description

Yellow needle-like crystals; burning, sweet odor; [CHEMINFO]

Sources/Uses

Used as a "color test for pine wood" and in the synthesis of organic chemicals; [HSDB]

Comments

m-Nitroaniline is in the ACGIH table of "Industrial Chemicals for Which Methemoglobin Formation is the Principal Cause of Toxicity." It emits toxic fumes of nitrogen oxides when heated. Methemoglobinemia has been reported after acute exposure and liver injury after chronic exposure. m-Nitroaniline is toxic after ingestion, inhalation, and skin exposure. [HSDB] Can induce methemoglobinemia; [ICSC]

Exposure Assessment
BEI

Methemoglobin in blood = 1.5% of hemoglobin during or at end of shift. [ACGIH]

Vapor Pressure

9.56E-5 mm Hg

Explanatory Notes

mp = 114 deg C; bp = 306 deg C (decomposes); Flash point = 199 deg C;

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

Methemoglobinemia

Methemoglobinemia, Primary

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: