Agent Name

2,3-Dichlorohexafluoro-2-butene

CAS Number

303-04-8

Formula

C4-Cl2-F6

Major Category

Other Classes

Synonyms

2,3-Dichloro-1,1,1,4,4,4-hexafluorobutene-2; 2,3-Dichlorohexafluorobutene-2; CFC 1316; CFC 1316 mxx; DCHFB; 2,3-Dichlorohexafluorobut-2-ene; 2-Butene, 2,3-dichloro-1,1,1,4,4,4-hexafluoro-; 2-Butene, 2,3-dichlorohexafluoro-; [ChemIDplus]

Category

Halogenated Aliphatics, Unsaturated

Description

Colorless liquid; [Aldrich MSDS]

Comments

Mildly irritating to rabbit skin; Positive results for skin sensitization in mice using local lymph node assay; [EPA TSCATS] Causes acute pulmonary edema in inhalation lethal-concentration studies of dogs; Causes ataxia and respiratory consolidation in inhalation lethal-concentration studies of monkeys; Causes general anesthesia, dyspnea, and cyanosis in inhalation lethal-concentration studies of rats and mice; [RTECS] Causes burns and lachrymation; Inhalation may cause corrosive injuries to upper respiratory tract and lungs; Highly toxic by inhalation; [Aldrich MSDS]

Exposure Assessment
Lethal Concentration

LC50 (rat) = 16 ppm/4hr

Adverse Effects
Lacrimator

Yes

Toxic Pneumonitis

Yes

Neurotoxin

CNS Solvent Syndrome

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: