Agent Name

n-Heptane

CAS Number

142-82-5

Formula

C7-H16

Major Category

Solvents

Synonyms

Dipropyl methane; Dipropylmethane; Eptani [Italian]; Gettysolve-C; Heptan [Polish]; Heptanen [Dutch]; Heptyl hydride; Skellysolve C; n-Heptane; [ChemIDplus] UN1206

Category

Aliphatics, Saturated (<C12)

Description

Colorless liquid with a gasoline-like odor; [NIOSH]

Sources/Uses

"Standard for octane-rating determinations (pure normal heptane has zero octane number) anesthetic, solvent, organic synthesis, preparation of laboratory reagents." [HSDB]

Exposure Assessment
Skin Designation (ACGIH)

Insufficient data

TLV (ACGIH)

400 ppm

STEL (ACGIH)

500 ppm

PEL (OSHA)

500 ppm

MAK

500 ppm

IDLH (NIOSH)

750 ppm

Excerpts from Documentation for IDLHs

Other human data: Inhalation of 1,000 ppm for 6 minutes was associated with slight dizziness [Patty and Yant 1929]. Exposure to 5,000 ppm for 4 minutes produced complaints of nausea, a loss of appetite, vertigo, and incoordination [Patty and Yant 1929]. A 15minute exposure to 5,000 ppm produced a state of intoxication characterized by uncontrolled hilarity in some individuals and in others a stupor lasting for 30 minutes after the exposure [Patty and Yant 1929].

Vapor Pressure

46 mm Hg

Odor Threshold Low

40 ppm

Odor Threshold High

547 ppm

Lethal Concentration

LC50 (rat) = 103,000 mg/m3/4H

Explanatory Notes

Detection odor threshold from AIHA (mean = 230 ppm); Flash point = -4 deg C; TLVs for all heptane isomers (108-08-7, 142-82-6, 565-59-3, 589-34-4, 590-35-2, and 591-76-4); [ACGIH] PEL and MAK for 142-82-6 only;

Flammability (NFPA)

3: May ignite at ambient temperature

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

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Health Studies

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: