Agent Name

Isopropylidene glycerol

Alternative Name

2,2-Dimethyl-1,3-dioxolane-4-methanol

CAS Number

100-79-8

Formula

C6-H12-O3

Major Category

Solvents

Synonyms

2,2-Dimethyl-1,3-dioxolane-4-methanol; 1,2-Isopropylideneglycerin; 1,2-Isopropylideneglycerol; 1,2-O,O-Isopropylideneglycerin; 1,2-O-Isopropylideneglycerol; 2,2-Dimethyl-1,3-dioxolan-4-yl methanol; 2,2-Dimethyl-4-(hydroxymethyl)-1,3-dioxacyclopentane; 2,2-Dimethyl-4-hydroxymethyldioxolane; 2,2-Dimethyl-4-oxymethyl-1,3-dioxolane; 2,2-Dimethyl-5-hydroxymethyl-1,3-dioxolane; 2,3-(Isopropylidenedioxy)propanol; 2,3-Isopropylideneglycerol; 4-Hydroxymethyl-2,2-dimethyl-1,3-dioxolane; Acetone glycerol; Acetone monoglycerol ketal; Acetone, cyclic (hydroxymethyl)ethylene acetal; Dioxolan; GIE; Glycerinisopropylidene ether; Glycerol acetonide (VAN); Glycerol dimethylketal; Glycerol, 1,2-O-isopropylidene; Glycerolacetone; Solketal; alpha,beta-Isopropylideneglycerol; 1,3-Dioxolane-4-methanol, 2,2-dimethyl-; [ChemIDplus]

Category

Other Solvents

Description

Nearly odorless liquid; [Merck Index] Colorless oily liquid; Odorless; [ICSC]

Sources/Uses

Used as solvent, plasticizer, and pharmaceutical aid (solubilizing and suspending agent); [Merck Index]

Comments

An eye irritant; Causes change in heart rate and blood pressure in intravenous lethal-dose studies of rats and rabbits; [RTECS] An eye irritant; [ICSC] May cause irritation; [Alfa Aesar MSDS] See "1,3-Dioxolane."

Exposure Assessment
Vapor Pressure

107 mm Hg

Flammability (NFPA)

3: May ignite at ambient temperature

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

Links to Other NLM Databases
Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: