Agent Name

Methyl nitrite

CAS Number

624-91-9

Formula

C-H3-N-O2

Major Category

Nitrogen Compounds

Synonyms

Nitrous acid, methyl ester; [ChemIDplus] UN2455

Category

Nitrates and Nitrites

Description

A liquid or gas; [CAMEO]

Sources/Uses

Used to synthesize nitrite and nitroso esters and as a rocket propellant; [HSDB]

Comments

Caused methemoglobinemia in two workers at a phenylpropanolamine production plant; [Abstract in PubMed and NIOSHTIC # 197071] Evaporating liquid can cause frostbite; [CAMEO]

Reference Link

Methemoglobinemia: an occupational hazard of phenylpropanolamine production

Exposure Assessment
BEI

Methemoglobin in blood = 1.5% of hemoglobin during or at end of shift. [ACGIH]

Lethal Concentration

LC50 (rat) = 176 ppm/4h

Adverse Effects
Methemoglobinemia

Methemoglobinemia, Primary

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: