Agent Name

2-Iodoacetamide

CAS Number

144-48-9

Formula

C2-H4-I-N-O

Major Category

Nitrogen Compounds

Synonyms

Iodoacetamide; Monoiodoacetamide; Surauto; Acetamide, 2-iodo-; [ChemIDplus]

Category

Other Nitrogen Compounds

Description

Crystalline solid; [Sigma-Aldrich MSDS]

Sources/Uses

An alkylating sulfhydryl reagent with action similar to iodoacetate; [ChemIDplus]

Comments

Causes ulceration or bleeding from the stomach and other GI changes in 74-week intermittent oral studies of rats; [RTECS] May cause irritation; May cause skin and respiratory sensitization; Toxic by ingestion; [Sigma-Aldrich MSDS] See "Chloroacetamide."

Reference Link

Biochemist's occupational allergic contact dermatitis from iodoacetamide and acrylamide.

Exposure Assessment
Vapor Pressure

0.00506 mm Hg

Adverse Effects
Skin Sensitizer

Yes

Links to Other NLM Databases
Toxicity Information

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Chemical Information

Search ChemIDplus

Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: