Agent Name

2-Methylfuran

CAS Number

534-22-5

Formula

C5-H6-O

Major Category

Other Classes

Synonyms

5-Methylfuran; Silvan [Czech]; Sylvan; alpha-Methylfuran; Furan, 2-methyl-; Methylfuran; [ChemIDplus] 2-Metilfurano (Spanish DOT); Methyl-2 furanne (French DOT); [CAMEO] UN2301

Category

Ethers, Other

Description

Clear colorless liquid with an ethereal odor; [CAMEO] Clear light yellow liquid; [Sigma-Aldrich MSDS]

Sources/Uses

Used as flavoring agent or adjuvant; [FDA]

Comments

Causes liver changes and somnolence in inhalation studies of rats; [RTECS] Furan-substituted aliphatic hydrocarbons have not been evaluated for safe use as flavoring agents due to "unresolved toxicological concerns", mainly being the carcinogenicity of furan in animal experiments; [JECFA] Contains 0.024% BHT (CAS# 128-37-0) as a stabilizer; May cause irritation; Toxic by inhalation; [Sigma-Aldrich MSDS] See "Furan."

Exposure Assessment
Vapor Pressure

142 mm Hg

Lethal Concentration

LC50 (rat) = 500 ppm/4hr

Explanatory Notes

LC50 (rat) = 8,300 mg/m3/4hr; [RTECS]

Flammability (NFPA)

3: May ignite at ambient temperature

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

Hepatotoxin

Hepatotoxin, Secondary

Links to Other NLM Databases
Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: