Agent Name

Hydroxylamine

CAS Number

7803-49-8

Formula

H3-N-O

Major Category

Nitrogen Compounds

Synonyms

Oxammonium; [ChemIDplus]

Category

Other Nitrogen Compounds

Description

Highly hygroscopic white solid; Unstable; Quickly decomposed at room temperature (especially by atmospheric moisture and carbon dioxide); mp = 33 deg C; [Merck Index]

Sources/Uses

Used as a reducing agent, antioxidant, chemical intermediate, and termination agent in polymers; used in the photography, chemistry, textile, leather, paint, soap, rubber, and plastics industries; [HSDB] Hydroxylamine sulfate used in photography (color neutralizing bath); [www.ci.tucson.az.us/arthazards/medium.html]

Comments

Crystals cause first degree burns on short exposure. [CHRIS] Reported toxic effects in humans include methemoglobinemia and skin sensitization. [HSDB] Allergic contact dermatitis reported in workers developing color photographs and handling laboratory reagents; [Kanerva, p. 1803] A skin and respiratory tract irritant; Corrosive to eyes; Can induce methemoglobinemia and consequent anemia; May cause skin sensitization; [ICSC] Occupational asthma confirmed in 2 workers exposed in paper recycling (de-inking process); [Malo] Reacts with water forming corrosive liquids; Rapidly decomposed at room temperature and by hot water; A strong reducing agent; Highly irritating or corrosive to skin and eyes; Reports of methemoglobinemia; [CAMEO] An irritant; May cause skin sensitization; Harmful by ingestion; High doses may cause methemoglobinemia; [Aldrich MSDS]

Reference Link

Occupational asthma and the paper recycling industry

Exposure Assessment
Vapor Pressure

9.75 mm Hg

Explanatory Notes

Vapor pressure at 47 degrees C = 9.75 mm Hg; [ICSC] Flash point = 265 deg F;

Reference Link

ICSC: Hydroxylamine

Adverse Effects
Skin Sensitizer

Yes

Asthma

Yes

Toxic Pneumonitis

Yes

Methemoglobinemia

Methemoglobinemia, Secondary

Anemia

Anemia, Hemolytic

Dermatotoxin

Skin Burns

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

Search ChemIDplus

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: