Agent Name

Toluene-2,5-diamine sulfate

Alternative Name

2,5-Diaminotoluene sulfate

CAS Number

615-50-9

Formula

C7-H10-N2.H2-O4-S

Major Category

Nitrogen Compounds

Synonyms

2,5-Diaminotoluene sulfate; 1,4-Benzenediamine, 2-methyl-, sulfate; 2-Methyl-1,4-benzenediamine sulfate; 2,5-Diaminotoluene sulphate; 2-Methyl-p-phenylenediamine sulfate; 2-Methyl-p-phenylenediamine sulphate; C.I. 76043 (VAN); CI 76043; Toluene-2,5-diamine sulphate; Toluene-2,5-diamine, sulfate; Toluylene-2,5-diamine sulfate; Toluylene-2,5-diamine sulphate; p-Diaminotoluene sulfate; p-Toluenediamine sulfate; p-Toluenediamine sulphate; p-Toluylenediamine sulfate; p-Toluylenediamine sulphate; p-Tolylenediamine sulfate; p-Tolylenediamine sulphate; [ChemIDplus] UN2811

Category

Amines, Aromatic

Description

Grey to white solid; [ICSC] Light brown powder; [Sigma-Aldrich MSDS]

Sources/Uses

Used in hair dyes; [ToxPlanet: EC - SCCS]

Comments

A mild skin and eye irritant; May cause skin sensitization; Can be absorbed through skin; [ICSC] A potent skin sensitizer, with positive patch test results observed in hairdressers with dermatitis; In 14-day feeding studies of rats, causes increased AST, CPK, LDH, and ALT at 60 mg/kg/day; [ToxPlanet: EC - SCCS] May cause irritation; Toxic by ingestion; [Sigma-Aldrich MSDS] See "2,5-Diaminotoluene."

Exposure Assessment
Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Toxic solid, organic, n.o.s."

Adverse Effects
Skin Sensitizer

Yes

Hepatotoxin

Hepatotoxin, Secondary

Methemoglobinemia

Methemoglobinemia, Secondary

Links to Other NLM Databases
Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: