Agent Name

3-Chloro-1-propanol

CAS Number

627-30-5

Formula

C3-H7-Cl-O

Major Category

Other Classes

Synonyms

1-Chloro-3-hydroxypropane; 3-Chloropropanol; 3-Chlorpropan-1-ol [German]; Trimethylene chlorohydrin; 1-Propanol, 3-chloro-; 3-Chloropropanol-1; [ChemIDplus] 1-Chloro-3-propanol; 3-Chloro-1-hydroxypropane; 3-Chloropropyl alcohol; Chloro-3 propanol-1 (French DOT); [CAMEO] Chloropropanol, 3-, 1-; [NTP] UN2849

Category

Halogenated Alcohols

Description

Colorless liquid; [CAMEO]

Sources/Uses

Used to make plastics, resins, and other chemicals; [CAMEO] Used as an intermediate in organic synthesis; [NTP] "An inhibitor of triosephosphate isomerase and glyceraldehyde 3-phosphate dehydrogenase." [ChemIDplus]

Comments

Causes muscle contraction or spasticity, ulceration of the stomach, and other liver changes in oral lethal-dose studies of mice; [RTECS] May cause skin, eye, and nasal irritation; Other symptoms may include vomiting, giddiness, dizziness, incoordination, visual disturbances, and coma; May be absorbed through skin; [NTP] An irritant; Harmful by ingestion; [Alfa Aesar MSDS] See "1-Chloro-2-propanol."

Exposure Assessment
Vapor Pressure

1.2 mm Hg

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

Hepatotoxin

Hepatotoxin, Secondary

Links to Other NLM Databases
Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: