Agent Name

3-Chloropropyltrimethoxysilane

CAS Number

2530-87-2

Formula

C6-H15-Cl-O3-Si

Major Category

Metals

Synonyms

(3-Chloropropyl)trimethoxysilane; (gamma-Chloropropyl)trimethoxysilane; 3-(Trimethoxysilyl)propyl chloride; A 143; CPS-M; KBM 703; SH 6076; Sila-Ace S 620; Silane (3-chloropropyl)tris(methoxy)-; Trimethoxy(3-chloropropyl)silane; Z 6076; Silane, (3-chloropropyl)trimethoxy-; [ChemIDplus] delta- Chloropropyltrimethoxysilane; Silicone A-143; [RTECS] CPTMO; Dynasylan CPTMO; gamma-Chloropropyltrimethoxysilane; Silquest A-143; [Reference #1]

Category

Metalloid Compounds (Silicon)

Description

Liquid; [Reference #1] Colorless liquid; [Alfa Aesar MSDS]

Sources/Uses

Used as a coupling agent for filled composites and industrial goods (textile goods); Used in closed systems to prevent loss due to rapid hydrolysis; [Reference #1]

Comments

Rapidly hydrolyzed producing 3 moles of methanol for every mole of silanetriol; Methanol is expected to cause any toxicity observed; Not a skin sensitizer in guinea pigs; A repeated-dose inhalation study produced no adverse effects at concentrations up to 100 ppm; Clinical observations in a micronucleus assay of mice include ataxia, tremors, prostration, myoclonic jerks, and vocalization; No reproductive or developmental toxicity observed in an inhalation study of rats at concentrations up to 100 ppm; [Reference #1] Reacts with water evolving methanol; A skin and strong eye irritant; [Alfa Aesar MSDS] See "Methyl alcohol." See "Trimethoxypropylsilane."

Reference Link

OECD SIDS: 3-Chloropropyltrimethoxysilane - 2006

Exposure Assessment
Vapor Pressure

0.39 mm Hg

Adverse Effects
Neurotoxin

Other CNS Neurotoxin

Links to Other NLM Databases
Toxicity Information

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Chemical Information

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Related Information in HazMap
Other Information

No other related information on this agent was found.