Agent Name

Mancozeb

CAS Number

8018-01-7

Formula

C4-H6-Mn-N2-S4.C4-H6-N2-S4-Zn

Major Category

Pesticides

Synonyms

Dithane, Dithane-Ultra, Fore, Green-Daisen M, Karamate, Mancofol, Mancozin, Manzate 200, Manzeb, Manzin Nemispor, Nemispot, Policar, Riozeb, Zimaneb; [EXTOXNET]

Category

Dithiocarbamates (Pesticide)

Description

Available as gray-yellow powder with a musty odorcontaining 80% product and 20% other surfactants and diluents; [AIHA]

Sources/Uses

A wide-spectrum fungicide used on seeds, fruits, vegetables, nuts, and field crops; [EXTOXNET] A protective eradicant and nonsystemic fungicide; [AIHA]

Comments

Classified as "practically nontoxic," mancozeb can cause occupational allergic contact dermatitis. [EXTOXNET] The EBCDCs (ethylenebisdithiocarbamates) can cause irritant and allergic contact dermatitis. EBDCs include ferbam, vapam, maneb, mancozeb, zineb, thiram, and ziram. They are also used as rubber accelerators. Ethylene thiourea (ETU), which may contaminate EBCDCs, is carcinogenic and teratogenic in animal experiments. [LaDou, p. 610] ETU is the major metabolite of EBDCs. [Krieger, p. 1690] In high-dose reproductive studies of animals, mancozeb causes testicular damage, fetal losses, and birth defects (hydrocephalus). [Frazier, p. 230-1] Potential for dermal sensitization; [AIHA: WEELs] See "Ethylene thiourea." See "Manganese" and linked occupational diseases.

Reference Link

EXTOXNET PIP - MANCOZEB

Exposure Assessment
WEEL

1 mg/m3

Reference Link

ICSC: Mancozeb

Adverse Effects
Skin Sensitizer

Yes

Neurotoxin

Parkinson's Syndrome

Reproductive Toxin

Yes

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: