Agent Name

Fungal cellulase

Major Category

Biological Agents

Category

Enzymes

Sources/Uses

Bakers add fungal enzymes to improve dough quality and shelf life. Enzymes added include alpha-amylase, cellulase, and hemicellulase (especially xylanase). [Elms J, et al. Prevalence of sensitisation to cellulase and xylanase in bakery workers. Occup Environ Med 2003;60:802-804]

Comments

Can cause immunologic contact urticaria; The risk is "extremely low where airbone exposure is properly controlled to minimize the risk of respiratory sensitization." [Kanerva, p. 482-3] Occupational asthma reported in a baker after exposure to amyloglucosidase/hemicellulase; [Malo]

Reference Link

Occupational contact urticaria from cellulase enzyme (No abstract available)

Adverse Effects
Skin Sensitizer

Yes

Asthma

Yes

Links to Other NLM Databases
Toxicity Information

Search TOXNET

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: