Agent Name

4-Ethyltoluene

CAS Number

622-96-8

Formula

C9-H12

Major Category

Solvents

Synonyms

1-Ethyl-4-methylbenzene; 1-Methyl-4-ethylbenzene; 4-Methylethylbenzene; p-Ethylmethylbenzene; p-Ethyltoluene; p-Methylethylbenzene; Benzene, 1-ethyl-4-methyl-; Toluene, p-ethyl-; [ChemIDplus] UN3295

Category

Aromatic Solvents

Description

Liquid; [Reference #1] Colorless liquid; [Alfa Aesar MSDS]

Comments

A skin and eye irritant in rabbits; Effects on mortality and clinical chemistry (increased ALT, alkaline phosphatase, and albumin), observed in 13-week oral studies of rats at 300 mg/kg/day; Male reproductive system effects (testicular atrophy and decreased spermatogenesis observed at 900 mg/kg; A 13-week inhalation study of rats demonstrated significant changes in liver and gonad weights at 4,800 mg/m3/day; [Reference #1] May cause irritation; Harmful by ingestion (may cause lung damage by aspiration); [Alfa Aesar MSDS] See "1-Ethyl-2-methylbenzene."

Reference Link

EPA ChAMP: Hazard Characterization: p-Ethyltoluene - 2009

Exposure Assessment
Vapor Pressure

3 mm Hg

Lethal Concentration

LC50 (rat) > 19,000 mg/m3/6hr

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Hydrocarbons, liquid, n.o.s."

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

Hepatotoxin

Hepatotoxin, Secondary

Links to Other NLM Databases
Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: