Agent Name


CAS Number




Major Category

Nitrogen Compounds


TEA; 2,2',2''-Nitrilotriethanol; 2,2',2''-Nitrilotris(ethanol); Alkanolamine 244; Biafine; Daltogen; Ethanol, 2,2',2'-nitrilotris-; Mobisyl; Nitrilotriethanol; Sterolamide; Sting-Kill; TEA (amino alcohol); Thiofaco T-35; Tri(hydroxyethyl)amine; Triethylamine, 2,2',2''-trihydroxy-; Triethylolamine; Trihydroxytriethylamine; Tris(2-hydroxyethyl)amine; Tris(beta-hydroxyethyl)amine; Trolamine; [ChemIDplus] 2,2',2?-Nitrilotriseth-anol; [Merck Index] Nitrilo-2,2',2"-triethanol; Tris (hydroxyethyl)amine;T-35; Nitrilotris (ethanol) [ToxPlanet: EPA - TSCATS] Tri-beta-hydroxy ethanolamine; [Fisher Scientific MSDS]




Highly hygroscopic, viscous liquid with a mild ammoniacal odor; Becomes brown on air and light exposure; mp = 21.57 deg C; [Merck Index] Light yellow viscous liqud; Hygroscopic; [Fisher Scientific MSDS]


Used as an intermediate for surface active agents, textile specialties, waxes, polishes, herbicides, petroleum demulsifiers, toilet goods, cement additives, cutting oils, and other chemicals, for increasing penetration of organic liquids into wood and paper, producing lubricants for textile industry, making emulsions with mineral oils, vegetable oils, paraffin, and waxes, as solvent for casein, shellac, dyes, and natural rubber, for wool scouring, as water-repellent for textiles, dispersion agent, corrosion inhibitor, softening agent, emulsifier, humectant, plasticizer, chelating agent, rubber accelerator, in amino resin adhesives formulations, to recover hydrogen sulfide from sour natural gases and sour crude petroleum, in cement production (milling process and to improve the flow and setting properties), as lubricant additive, initiator for poly triol production, and pharmaceutic aid (alkalizing agent; [HSDB] Used as an emulsifier and surfactant in various cleaning products, polishes, metalworking fluids, paints, and printing inks, and as an alkalinizing agent in personal care products; [REPROTOX] Used as stabilizer or inhibitor in pre-emergence pesticides; [ExPub: EPA - TSCATS] Used in the chemical, fuel, leather processing, paper-pulp-board, paints-lacquers-varnishes, polymers, photographic, textile processing, cosmetics, construction, extraction, refining, and processing of metals, and personal-domestic use industries; Used to make herbicides and polyurethane foam, as an anti-freeze agent, construction materials additive, corrosion inhibitor, intermediate, lubricant and additive, laboratory chemical, dustbinding agent, pH regulator, photochemical, surface-active agent, process regulator, tanning agent, vulcanizing agent, catalyst, additive in metal working fluids, in cement grinding, and gas purification; [IUCLID]


Occupational asthma and allergic contact dermatitis in machinists and photographers; [See Reference; Marks, p. 159-60] Animals sustain liver and kidney damage after high-dose feeding studies. [ACGIH] A skin, eye, and respiratory tract irritant; May cause skin sensitization; [ICSC] Low acute toxicity, with median oral LD50 values of 4,190-11,260 mg/kg in rats and 5,300-8,000 mg/kg in guinea pigs; Median dermal LD50 greater than 2,000 mg/kg in rabbits; No evidence of skin sensitization in animal studies or in a group of 64 human volunteers; Low incidence of skin sensitization reported in humans; Not carcinogenic, a developmental toxicant, or toxic to the reproductive system; [OECD SIDS] An eye irritant; May cause skin sensitization; Chronic exposure may cause liver and kidney injury; [Fisher Scientific MSDS]

Reference Link

Occupational asthma caused by ethanolamines

Exposure Assessment
Skin Designation (ACGIH)

Insufficient data


5 mg/m3


5 mg/m3, inhalable fraction

Vapor Pressure

3.59E-6 mm Hg

Explanatory Notes

Flash point = 179 deg C;

Reference Link

ICSC: Triethanolamine

Flammability (NFPA)

1: Must be preheated

Adverse Effects
Skin Sensitizer





Hepatotoxin, Secondary

IARC Carcinogen

Not Classifiable

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information


Chemical Information

Search ChemIDplus

Biomedical References

Search PubMed

Related Information in HazMap

Occupational diseases associated with exposure to this agent:


Industrial Processes with risk of exposure: