Agent Name

Fluorescein-5-isothiocyanate

Alternative Name

FITC

CAS Number

3326-32-7

Formula

C21-H11-N-O5-S

Major Category

Dyes

Synonyms

Spiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one, 3',6'-dihydroxy-5-isothiocyanato-; [ChemIDplus] 3',6'-dihydroxy-5-isothiocyanatospiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one; FITC; [Merck Index]

Category

Indicator Dyes

Description

Orange solid; [Merck Index] Orange powder; [Alfa Aesar MSDS]

Sources/Uses

Used as a fluorescent indicator to probe biological systems and monitor sewage; [Merck Index]

Comments

Causes cutaneous sensitization (experimental) and effects on inflammation in 3-day intermittent dermal studies of mice; [RTECS] May cause irritation; May cause skin and respiratory sensitization; [Alfa Aesar MSDS]

Reference Link

Systemic migration of dendritic cells during contact sensitization.

Adverse Effects
Skin Sensitizer

Yes

Links to Other NLM Databases
Toxicity Information

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Chemical Information

Search ChemIDplus

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: