| Agent Name | 6-Methylhept-5-en-2-one |
|---|---|
| CAS Number | 110-93-0 |
| Formula | C8-H14-O |
| Major Category | Other Classes |
| Synonyms | Methylheptenone; 2-Methyl-2-hepten-6-one; 2-Methyl-6-oxo-2-heptene; 2-Oxo-6-methylhept-5-ene; 6-Methyl-5-hepten-2-one; 6-Methyl-5-hepten-2-one (natural); Sulcatone; 5-Hepten-2-one, 6-methyl-; Methyl heptenone; [ChemIDplus] 2-Methylhepten-2-on-6; 6-Methyl-delta5-hepten-2-one; [IUCLID] UN1224 |
| Category | Aliphatic Ketones, Other |
| Description | Colorless to yellowish liquid with a strong odor; [OECD SIDS] |
| Sources/Uses | Used as flavor enhancer; [FDA] Used mainly for chemical synthesis (closed systems); Also used in cleaning agents and as a flavor or aroma additive in cosmetics and food; [OECD SIDS] |
| Comments | No skin sensitization observed in study of 25 volunteers; [IUCLID] Mild skin irritation observed in rabbits (nearly reversed in 48 hours); Causes mild corneal opacity and mild conjunctival redness in rabbits 24 hours following application (completely reversed within 8 days); Not a skin sensitizer in guinea pigs; Significant effects to sperm, significantly increased absolute and relative liver and kidney weights, decreased size of the testes and epididymis, and histopathological changes of the liver, kidney, and testes observed in 90-day oral study of rats at the highest tested dose (1,000 mg/kg/day, with a LOAEL of 50 mg/kg/day); [OECD SIDS] Safe when used as a flavoring agent in food; [JECFA] May cause irritation; [Sigma-Aldrich MSDS] |
| Exposure Assessment | |
| Vapor Pressure | 0.75 mm Hg |
| Lethal Concentration | LC50 (rat) > 13,960 mg/m3/4hr |
| Explanatory Notes | The Guide in the Emergency Response Guidebook is for "Ketones, liquid, n.o.s." |
| Adverse Effects | |
| Hepatotoxin | Hepatotoxin, Secondary |
| Links to Other NLM Databases | |
| Toxicity Information | |
| Chemical Information | |
| Related Information in HazMap | |
| Other Information | No other related information on this agent was found. |
Agent Name
6-Methylhept-5-en-2-one
CAS Number
110-93-0
Formula
C8-H14-O
Major Category
Other Classes
Synonyms
Methylheptenone; 2-Methyl-2-hepten-6-one; 2-Methyl-6-oxo-2-heptene; 2-Oxo-6-methylhept-5-ene; 6-Methyl-5-hepten-2-one; 6-Methyl-5-hepten-2-one (natural); Sulcatone; 5-Hepten-2-one, 6-methyl-; Methyl heptenone; [ChemIDplus] 2-Methylhepten-2-on-6; 6-Methyl-delta5-hepten-2-one; [IUCLID] UN1224
Category
Aliphatic Ketones, Other
Description
Colorless to yellowish liquid with a strong odor; [OECD SIDS]
Sources/Uses
Used as flavor enhancer; [FDA] Used mainly for chemical synthesis (closed systems); Also used in cleaning agents and as a flavor or aroma additive in cosmetics and food; [OECD SIDS]
Comments
No skin sensitization observed in study of 25 volunteers; [IUCLID] Mild skin irritation observed in rabbits (nearly reversed in 48 hours); Causes mild corneal opacity and mild conjunctival redness in rabbits 24 hours following application (completely reversed within 8 days); Not a skin sensitizer in guinea pigs; Significant effects to sperm, significantly increased absolute and relative liver and kidney weights, decreased size of the testes and epididymis, and histopathological changes of the liver, kidney, and testes observed in 90-day oral study of rats at the highest tested dose (1,000 mg/kg/day, with a LOAEL of 50 mg/kg/day); [OECD SIDS] Safe when used as a flavoring agent in food; [JECFA] May cause irritation; [Sigma-Aldrich MSDS]
Exposure Assessment
Vapor Pressure
0.75 mm Hg
Lethal Concentration
LC50 (rat) > 13,960 mg/m3/4hr
Explanatory Notes
The Guide in the Emergency Response Guidebook is for "Ketones, liquid, n.o.s."
Adverse Effects
Hepatotoxin
Hepatotoxin, Secondary
Links to Other NLM Databases
Toxicity Information
Chemical Information
Related Information in HazMap
Other Information
No other related information on this agent was found.