Agent Name

6-Hydroxydopamine hydrochloride

CAS Number

28094-15-7

Formula

C8-H11-N-O3.Cl-H

Major Category

Other Uses

Synonyms

2,4,5-Trihydroxyphenethylamine hydrochloride; 5-(2-Aminoethyl)-1,2,4-benzenetriol hydrochloride; 6-Hydroxydopamine chloride; Oxidopamine HCl; Oxidopamine hydrochloride; 1,2,4-Benzenetriol, 5-(2-aminoethyl)-, hydrochloride; 5-(2-Aminoethyl)-4-hydroxypyrocatechol hydrochloride; [ChemIDplus] 6-OHDA; 2,5-Dihydroxytyraminehydrochloride; 2-(2,4,5- Trihydroxyphenyl)ethylaminehydrochloride; 2,4,5-Trihydroxyphenethylaminehydrochloride; [Sigma-Aldrich MSDS]

Category

Biochemical Research

Description

Beige hygroscopic solid; [CAMEO] Light brown powder; [Sigma-Aldrich MSDS]

Sources/Uses

"Depletes neurons of catecholamines." [NTP]

Comments

Affects dopamine levels in striatum of CNS causing rigidity in acute intracerebral studies of rats; [RTECS] A skin and strong eye irritant; Targets the nerves, heart, and GI tract; [Sigma-Aldrich MSDS]

Adverse Effects
Neurotoxin

Other CNS Neurotoxin

Links to Other NLM Databases
Toxicity Information

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Chemical Information

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Other Information

No other related information on this agent was found.