Agent Name

Trichloronate

CAS Number

327-98-0

Formula

C10-H12-Cl3-O2-P-S

Major Category

Pesticides

Synonyms

5082A; Agrisil; Agritox; BAY 37289; Bayer 37289; Bayer 5081; Bayer S 4400; Chemagro 37289; ENT 25,712; Ethyl trichlorophenylethylphosphonothioate; Fenophosphon; Fitosol; O-Aethyl-O-(2,4,5-trichlorphenyl)-aethylthionophosphonat [German]; O-Ethyl O-(2,4,5-trichlorophenyl) ethylthiophosphonate; O-Ethyl O-2,4,5-trichlorophenyl ethylphosphonothioate; OMS 412; OMS 578; Phenol, 2,4,5-trichloro-, O-ester with O-ethyl ethylphosphonothioate; Phytosol; Richloronate; S 4400; Stauffer N-3049; Trichloronat; Wirkstoff 37289; Phosphonothioic acid, ethyl-, O-ethyl O-(2,4,5-trichlorophenyl) ester; [ChemIDplus] UN3018

Category

Organophosphate Insecticides

Description

Amber liquid; Formulated as emulsifiable concentrate, granules, or seed dressing powder; [HSDB] Liquid; [Aldrich MSDS]

Sources/Uses

Used as an insecticide against vegetable fly larvae and soil pests; Not marketed in the USA or Canada; [HSDB] No active product registrations in the US; [NPIRS]

Comments

A small number of the organophosphates (OPs) can Induce Delayed Neuropathy (OPIDN). OPIDN usually occurs after ingestion and is usually nonoccupational. [Levy, p. 431] A highly toxic cholinesterase inhibitor; Reports of delayed neurotoxicity; [CAMEO] May cause irritation; A highly toxic cholinesterase inhibitor; Readily absorbed through skin (toxic); May be fatal by ingestion; Targets CNS, heart, blood, and eyes; [Aldrich MSDS] The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline. [TLVs and BEIs]

Exposure Assessment
BEI

Acetylcholinesterase activity in red blood cells = 70% of individual's baseline; Butylcholinesterase activity in serum or plasma = 60% of individual's baseline; Sample at end of shift; [TLVs and BEIs]

Vapor Pressure

1.5E-5 mm Hg

Lethal Concentration

LCLo (rat) = 700 mg/m3/4hr

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Organophosphorus pesticide, liquid, toxic."

Adverse Effects
Neurotoxin

Motor Neuropathy

Other Poison

Organophosphate

Links to Other NLM Databases
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Diseases

Occupational diseases associated with exposure to this agent:

Processes

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