Agent Name

4,4'-Methylenebis(2,6-di-tert-butylphenol)

CAS Number

118-82-1

Formula

C29-H44-O2

Major Category

Other Classes

Synonyms

2,2',6,6'-Tetra-tert-butyl-4,4'-methylenediphenol; 4,4'-Methylenebis(2,6-bis(1,1-dimethylethyl)phenol); 4,4'-Methylenebis(2,6-di-t-butylphenol); Antioxidant E 702; Binox M; Di(4-hydroxy-3,5-di-tert-butylphenyl)methane; E 702; Ethyl 702; Etil 702; Ionox 220; Ionox 220 Antioxidant; L 3MB1; LZ-MB 1; MB 1 (Antioxidant); MB 1 (antioxidant) (VAN); Phenol, 4,4'-methylenebis(2,6-di-tert-butyl-; Phenol, 4,4'-methylenebis(2,6-bis(1,1-dimethylethyl)-; [ChemIDplus] 4,4'-Dihydroxy-3,3',5,5'-tetra-tert-butyl-diphenylmethan; Alkylated phenol; Ethanox 702; [IUCLID]

Category

Other Aromatic Compounds

Description

White or yellow powder; [Alfa Aesar MSDS]

Sources/Uses

Used in the fuel, polymers, and lubricant blending industries; Used as an antioxidant additive in petroleum-based lubricants; [IUCLID]

Comments

A skin and eye irritant in rabbits; No mortality or gross lesions observed in oral lethal-dose study of rats at 5,000 mg/kg; Another lethal-dose study of rats produced increasing severity of hepatic degeneration in animals that died (doses of 4,700-36,000 mg/kg); No mortality or symptoms of systemic toxicity observed in dermal lethal-dose study of rats at doses up to 36,000 mg/kg; [IUCLID] Causes ulceration or bleeding from the large intestine and fibrous hepatitis (cirrhosis, post necrotic scarring) in 2-year constant feeding studies of dogs; [RTECS] A skin and strong eye irritant; [Alfa Aesar MSDS] See "2,2'-Methylenebis(6-t-butyl-4-ethylphenol)."

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

Links to Other NLM Databases
Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Related Information in HazMap
Other Information

No other related information on this agent was found.