Agent Name

4-Hydroxyaminoquinoline-1-oxide

CAS Number

4637-56-3

Formula

C9-H8-N2-O2

Major Category

Other Uses

Synonyms

4-(Hydroxyamino)quinoline 1-oxide; 4-(Hydroxyamino)quinoline-1-oxide; 4-Hydroxyaminoquinoline N-oxide; 4HAQO; Hydroxylamine, N-(4-quinolyl)-, 1'-oxide; 4-Quinolinamine, N-hydroxy-, 1-oxide; Quinoline, 4-(hydroxyamino)-, 1-oxide; [ChemIDplus] 4-Quinolinamine-N-hydroxy-1-oxide; Quinolinaminehydroxyoxide,4-,N-,1-; [NTP]

Category

Biochemical Research

Description

Gold solid; [CAMEO]

Sources/Uses

"A potent mutagen and carcinogen. It is a reduction product of 4-NITROQUINOLINE-1-OXIDE. It binds with nucleic acids and inactivates both bacteria and bacteriophage." [ChemIDplus]

Comments

Causes focal lung fibrosis and other liver changes in intravenous lethal-dose studies of rats (LDLo = 5 mg/kg); [RTECS] See "4-Nitroquinoline-N-oxide." See "Quinoline."

Exposure Assessment
Vapor Pressure

2.28E-8 mm Hg

Links to Other NLM Databases
Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Related Information in HazMap
Other Information

No other related information on this agent was found.