Agent Name

Kynurenic acid

CAS Number

492-27-3

Formula

C10-H7-N-O3

Major Category

Other Uses

Synonyms

4-Hydroxyquinaldic acid; 4-Hydroxyquinaldinic acid; 4-Hydroxyquinoline-2-carboxylic acid; Kinurenic acid; Kynuronic acid; Quinurenic acid; 2-Quinolinecarboxylic acid, 4-hydroxy-; Quinaldic acid, 4-hydroxy- (8CI); [ChemIDplus]

Category

Biochemical Research

Description

Yellow solid; [Merck Index] Yellow needles; [Alfa Aesar MSDS]

Sources/Uses

A metabolite of tryptophan found in the urine of some animals; Used in nutritional studies of vitamin B deficiency; [Merck Index] "A broad-spectrum excitatory amino acid antagonist used as a research tool." [ChemIDplus]

Comments

Causes anticonvulsant behavior in acute intracerebral and intraperitoneal studies of mice; Causes other degenerative changes of brain and coverings in acute intracerebral studies of rats; Causes analgesia in acute intraspinal studies of rats; [RTECS] A skin and strong eye irritant; [Alfa Aesar MSDS] See "Quinoline."

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