Agent Name

Isophorone diisocyanate

CAS Number

4098-71-9

Formula

C12-H18-N2-O2

Major Category

Plastics & Rubber

Synonyms

IPDI; 3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl-isocyanate; Isophorone diamine diisocyanate; [NIOSH]

Category

Diisocyanates

Description

Colorless to slightly yellow liquid with a pungent odor; [NIOSH]

Sources/Uses

Used in polyurethane paints, varnishes, and elastomers; [HSDB] Occupational asthma reported in spray painter; [Malo]

Comments

May cause skin sensitization; [ICSC] Danger of sensitization of the airways and skin; [MAK] See "DIISOCYANATES."

Reference Link

Isophorone diisocyanate induced respiratory disease (IPDI).

Exposure Assessment
Skin Designation (ACGIH)

Insufficient data

TLV (ACGIH)

0.005 ppm

MAK

0.005 ppm

Vapor Pressure

0.0003 mm Hg

Reference Link

ICSC: Isophorone diisocyanate

Adverse Effects
Skin Sensitizer

Yes

Asthma

Yes

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Biomedical References

Search PubMed

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: