Agent Name

alpha-Naphthoflavone

CAS Number

604-59-1

Formula

C19-H12-O2

Major Category

Other Uses

Synonyms

2-Phenyl-4H-naphtho(1,2-b)pyran-4-one; 7,8-BF; 7,8-Benzoflavone; Benzo(h)flavone; alpha-Naphthylflavone; 2-Phenylbenzo(h)chromen-4-one; 4H-Naphtho(1,2-b)pyran-4-one, 2-phenyl-; [ChemIDplus]

Category

Biochemical Research

Description

Solid; [Sigma-Aldrich MSDS]

Sources/Uses

"alpha-Naphthoflavone is a potent inhibitor of the enzyme aromatase, the enzyme that converts testosterone to estrogen. alpha-Naphthoflavone has been shown to cause abnormal testicular development in young chickens." [Wikipedia]

Comments

Causes lung changes, liver changes, thyroid hypofunction, and multiple enzyme effects in acute intraperitoneal studies of rats; [RTECS] May cause irritation; [Sigma-Aldrich MSDS]

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