Agent Name

Lead chromate

CAS Number

7758-97-6

Formula

Cr-O4.Pb

Major Category

Metals

Synonyms

Chrome yellow; C.I. Pigment yellow; [ACGIH]

Category

Lead Compounds, Inorganic

Description

Bright yellow solid; Low water solubility (5.8 ug/L); [ACGIH]

Sources/Uses

Used as a pigment; Chrome yellow is PbCrO4. Chrome green and chrome red also contain PbCrO4. [ACGIH] Used as a pigment in paints, ceramics, rubber and plastics, and fabric printing; [HSDB]

Comments

Despite the limited evidence for lead chromate causing cancer in humans, there is ample evidence in humans and animals that all Cr(VI) compounds, both soluble and insoluble, are capable of causing lung cancer. Lead poisoning can occur in exposed workers. [ACGIH] See "Lead" and linked occupational diseases. "See "Chromium" and linked occupational diseases.

Restricted

In 1977 the Consumer Product Safety Commission banned "lead containing paint" prohibiting the use of such paint on products to which consumers are exposed after sale. [ATSDR ToxFAQs, Toxicological Profile, Regulations and Advisories]

Exposure Assessment
BEI

Lead in blood = 200 ug/L (20 ug/100 ml); sampling time not critical; [ACGIH] See "Chromium" for BEI of chromium (VI) water-soluble fume.

Skin Designation (ACGIH)

Insufficient data

Bioaccumulates

Yes

TLV (ACGIH)

0.0002 mg/m3, as Cr(VI), inhalable particulate matter

STEL (ACGIH)

0.0005 mg/m3, as Cr(VI), inhalable particulate matter

Explanatory Notes

Melting point = 844 deg C; [ACGIH]

Adverse Effects
Skin Sensitizer

Yes

Asthma

Yes

Neurotoxin

Motor Neuropathy

Hepatotoxin

Hepatotoxin, Secondary

Nephrotoxin

Yes

Reproductive Toxin

Yes

Dermatotoxin

Skin Burns

IARC Carcinogen

Known Carcinogen

NTP Carcinogen

Human Carcinogen

ACGIH Carcinogen

Confirmed Human

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: