Agent Name

Lead chromate

CAS Number

7758-97-6

Formula

Cr-O4.Pb

Major Category

Metals

Synonyms

Chrome yellow; C.I. Pigment yellow; [ACGIH]

Category

Lead Compounds, Inorganic

Description

Yellow crystals or powder; [ACGIH]

Sources/Uses

Used as a pigment; Chrome yellow is PbCrO4. Chrome green and chrome red also contain PbCrO4. [ACGIH] Used as a pigment in paints, ceramics, rubber and plastics, and fabric printing; [HSDB]

Comments

Because of its "extreme insolubility," the relative toxicity of this compound has been debated. Epidemiology studies in lead chromate workers have shown evidence of excess lung cancer. It can be corrosive to living tissue. Lead poisoning can occur in exposed workers. [ACGIH] See "Lead" and linked occupational diseases. "See "Chromium" and linked occupational diseases.

Restricted

In 1977 the Consumer Product Safety Commission banned "lead containing paint" prohibiting the use of such paint on products to which consumers are exposed after sale. [ATSDR ToxFAQs, Toxicological Profile, Regulations and Advisories]

Exposure Assessment
BEI

Lead in blood = 200 ug/L (20 ug/100 ml); sampling time not critical; [ACGIH]

Skin Designation (ACGIH)

Insufficient data

Bioaccumulates

Yes

TLV (ACGIH)

0.01 mg/m3, as Cr ( 0.05 mg/m3, as Pb)

Explanatory Notes

See "2017 Notice of Intended Changes." [TLVs and BEIs]

Adverse Effects
Skin Sensitizer

Yes

Asthma

Yes

Neurotoxin

Motor Neuropathy

Hepatotoxin

Hepatotoxin, Secondary

Nephrotoxin

Yes

Reproductive Toxin

Yes

Dermatotoxin

Skin Burns

IARC Carcinogen

Known Carcinogen

NTP Carcinogen

Human Carcinogen

ACGIH Carcinogen

Suspected Human

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: