Agent Name

Naphthalene diisocyanate

Alternative Name

NDI

CAS Number

3173-72-6

Formula

C12-H6-N2-O2

Major Category

Plastics & Rubber

Synonyms

1,5-Diisocyanatonaphthalene; 1,5-Naphthalene diisocyanate;1,5-Naphthalene ester of isocyanic acid; NDI; [NIOSH]

Category

Diisocyanates

Description

White to light-yellow, crystalline flakes; [NIOSH]

Sources/Uses

Occupational asthma reported in rubber manufacturing; [Malo]

Comments

May cause skin sensitization; [ICSC] "Biological monitoring of exposure to 1,5-naphthalene diisocyanate and 4,4'-methylenediphenyl diisocyanate." [PMID 16506043] See "DIISOCYANATES."

Reference Link

Isocyanate asthma: respiratory symptoms due to 1,5-naphthylene di-isocyanate

Exposure Assessment
Vapor Pressure

0.003 mm Hg

Reference Link

ICSC: Naphthalene 1,5-diisocyanate

Adverse Effects
Skin Sensitizer

Yes

Asthma

Yes

IARC Carcinogen

Not Classifiable

Links to Other NLM Databases
Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Biomedical References

Search PubMed

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: