Agent Name

Aprotinin

CAS Number

9087-70-1

Formula

C284-H432-N84-O79-S7

Major Category

Other Uses

Synonyms

Antagosan; Antikrein; Antilysin; Antilysine; Aprotinin; Aprotinin bovine; Aprotinina [INN-Spanish]; Aprotinine [INN-French]; Aprotininum [INN-Latin]; BPTI; Basic pancreatic trypsin inhibitor; Basic protease inhibitor; Bayer A 128; Contrykal; Fosten; Gordox; Inhibin; Iniprol; Kallikrein-trypsin inactivator; Kir richter; Kunitz and Northrop inhibitor; L-Arginyl-L-prolyl-L-aspartyl-L-phenylalanyl-L-cysteinyl-L-leucyl-L-glutamyl-L-prolyl-L-prolyl-L-tyrosyl-L-threonylglycyl-L-prolyl-L-cysteinyl-L-lysyl-L-alanyl-L-arginyl-L-isoleucyl-L-isoleucyl-L-arginyl-L-tyrosyl-L-; phenylalanyl-L-tyrosyl-L-asparaginyl-L-alanyl-L-lysyl-L-alanylglycyl-L-leucyl-L-cysteinyl-L-glutaminyl-L-threonyl-L-phenylalanyl-L-valyl-L-tyrosylglycylglycyl-L-cysteinyl-L-arginyl-L-alanyl-L-lysyl-L-arginyl-L-asparaginyl-L-asparaginyl-L-phenylalanyl-L-lysyl-L-seryl-L-alanyl-L-glutamyl-L-aspartyl-L-cysteinyl-L-methionyl-L-arginyl-L-threonyl-L-cysteinylglycylglycyl-L-alanine cyclic (5-55), (14-38), (30-51) tris(disulfide); Onquinin; Pancreatic basic trypsin inhibitor; Pancreatic trypsin inhibitor; Pancreatic trypsin inhibitor (Kunitz); Pantinol; Protimbin; RP 9921; RP-9921; Repulson; Riker 52G; Trascolan; Trasylol; Triazinin; Trypsin inhibitor; Trypsin-kallikrein inhibitor (Kunitz); Tzalol; Zymofren; Trypsin inhibitor, pancreatic basic; [ChemIDplus] Aprotinin, from bovine lung; [Sigma-Aldrich MSDS]

Category

Biochemical Research

Description

White powder; [Sigma-Aldrich MSDS]

Sources/Uses

A single chain polypeptide with 58 amino-acids found in blood and tissue; Used as a proteolytic inhibitor in radioimmunoassays of polypeptide hormones and as a therapeutic protease inhibitor; [Merck Index]

Comments

Causes somnolence and inflammation in acute intraperitoneal studies of mice and rats; Causes cardiomyopathy and elevated blood pressure in acute intravenous studies of rats; [RTECS]

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