Agent Name

Capsaicin

CAS Number

404-86-4

Formula

C18-H27-N-O3

Major Category

Biological Agents

Synonyms

(E)-8-Methyl-N-vanillyl-6-nonenamide; (E)-N-((4-Hydroxy-3-methoxyphenyl)-methyl)-8-methyl-6-nonenamide; 6-Nonenamide, (E)-N-((4-hydroxy-3-methoxy-phenyl)methyl)-8-methyl; 6-Nonenamide, 8-methyl-N-vanillyl-, (E)-; 6-Nonenamide, N-((4-hydroxy-3-methoxyphenyl)methyl)-8-methyl-, (E)-; 8-Methyl-N-vanillyl-6-nonenamide, (E)-; Capsaicine; Isodecenoic acid vanillylamide; N-((4-Hydroxy-3-methoxyphenyl)methyl)-8-methyl-6-nonenamide, (E)-; N-(4-Hydroxy-3-methoxybenzyl)-8-methylnon-trans-6-enamide; NGX 4010; NGX-4010; Qutenza; Styptysat; Zostrix; trans-8-Methyl-N-vanillyl-6-nonenamide; 6-Nonenamide, N-((4-hydroxy-3-methoxyphenyl)methyl)-8-methyl-, (6E)-; [ChemIDplus] (6E)- N-((4-Hydroxy-3-methoxyphenyl)methyl)-8-methyl-6-nonenamide; Axsain; Mioton; Zacin; [Merck Index] E-Capsaicin; trans- N-((4-Hydroxy-3-methoxyphenyl)methyl)-8-methyl-6-nonenamide; [RTECS]

Category

Plant Toxins

Description

Dark red solid with a volatile pungent odor; [HSDB] Formulated as dry powder, liquid, and liquid spray; [Reference #1] White crystalline solid; [Sigma-Aldrich MSDS]

Sources/Uses

Pungent component in capsicum species plants; Used in neurobiological research and as a topical analgesic; [Merck Index] Used as flavoring agent or adjuvant; [FDA] Used as a repellent for birds, voles, deer, rabbits, squirrels, insects, and attacking dogs indoors and outdoors for the protection of fruit and vegetable crops, ornamentals, and lawns; [Reference #1]

Comments

Causes local irritation and lachrymation; Skin contact results in erythema and burning without blistering; Intense tearing, pain, conjunctivitis, and blepharospasm may occur from eye contact; [HSDB] It is unlikely that pesticide products containing capsaicin will pose a significant threat to human health. Excessive exposure to capsaicin may cause some slight eye and skin irritation. [Reference #1]

Reference Link

EPA Pesticide Chemical Search

Exposure Assessment
Vapor Pressure

1.3E-8 mm Hg

Adverse Effects
Lacrimator

Yes

Links to Other NLM Databases
Health Studies

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Toxicity Information

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Chemical Information

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Processes

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