Agent Name

Ninhydrin

CAS Number

485-47-2

Formula

C9-H6-O4

Major Category

Other Classes

Synonyms

1,2,3-Indantrione monohydrate; 1,2,3-Indantrione, 2-hydrate; 2,2-Dihydroxy-1,3-indandione; 2,2-Dihydroxy-1H-indene-1,3(2H)-dione; Ninhydrin; Ninhydrin hydrate; Triketohydrindene hydrate; 1,3-Indandione, 2,2-dihydroxy-; 1H-Indene-1,3(2H)-dione, 2,2-dihydroxy-; Indan-1,2,3-trione; [ChemIDplus]

Category

Other Organic Compounds

Description

White to light yellow crystals or powder; [CAMEO]

Sources/Uses

Used as a laboratory reagent to detect amino and carboxyl groups in peptides and proteins; [Pirila P et al. Rhinitis caused by ninhydrin develops into occupational asthma. Eur Respir J. 1997, Aug;10(8):1918-21.]

Comments

Allergic contact dermatitis and occupational asthma reported in a forensic technician; [Malo] A skin, eye, and respiratory tract irritant; May cause skin sensitization; [ICSC]

Reference Link

Rhinitis caused by ninhydrin develops into occupational asthma

Exposure Assessment
Vapor Pressure

2.36E-7 mm Hg

Reference Link

Allergic contact dermatitis from ninhydrin in a forensic scientist

Adverse Effects
Skin Sensitizer

Yes

Asthma

Yes

Links to Other NLM Databases
Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: