Agent Name

beta-Cyclodextrin

CAS Number

7585-39-9

Formula

C42-H70-O35

Major Category

Biological Agents

Synonyms

Betadex; Cycloheptaamylose; Cycloheptaglucan; Cycloheptaglucosan; Cyclomaltoheptaose; Dextrin, beta-cyclo; Kleptose; Kleptose B; Rhodocap N; Ringdex B; Ringdex BL; Schardinger beta-dextrin; beta-Cycloamylose; beta-Cycloheptaamylose; beta-Dextrin; Cycloheptapentylose; [ChemIDplus] betaCD; BCD; beta-Schardinger dextrin; Cyclodextrin C; [JECFA]

Category

Polysaccharides

Description

White virtually odorless solid; [JECFA] White powder; [Sigma-Aldrich MSDS]

Sources/Uses

Permitted for use as an inert ingredient in non-food pesticide products; [EPA] Used as flavoring agent and formulation aid; [FDA] Used as a thickening agent and an encapsulation agent for food additives, flavoring, and vitamins; [JECFA]

Comments

Composed of 7 glucose units joined together; Acceptable daily intake (ADI) of 0-5 mg/kg; [JECFA] Causes zonal hepatitis and acute tubular necrosis in 52-week constant oral studies of rats; Causes diffuse and zonal hepatitis in 7-week constant oral studies of rats; [RTECS] Causes mild skin and eye irritation in rabbits; Not a skin sensitizer in guinea pigs; [Sigma-Aldrich MSDS] See "alpha-Cyclodextrin."

Exposure Assessment
Lethal Concentration

LC50 (rat) > 4,900 mg/m3/4hr

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

Links to Other NLM Databases
Toxicity Information

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Chemical Information

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Other Information

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