Agent Name

Bisbenzimidazole trihydrochloride

CAS Number

23491-45-4

Formula

C25-H24-N6-O.3Cl-H

Major Category

Dyes

Synonyms

Bisbenzimidazole; 33258 Hoechst; 4-(5-(4-Methyl-1-piperazinyl)(2,5'-bi-1H-benzimidazol)-2'-yl)phenol trihydrochloride; 4-(5-(4-Methyl-1-piperazinyl)(2,5'-bi-1H-benzimidazol)-2'-yl)phenol, trihydrochloride; Bisbenzimide; H 33258; HOE 33058; HOE 33258; Hoechst 33258; Hoechst Dye 33258; Phenol, 4-(5-(4-methyl-1-piperazinyl)(2,5'-bi-1H-benzimidazol)-2'-yl)-, trihydrochloride; Pibenzimol HCl; Phenol, 4-(5-(4-methyl-1-piperazinyl)(2,5'-bi-1H-benzimidazol)-2'-yl)-, hydrochloride (1:3); Phenol, p-(5-(5-(4-methyl-1-piperazinyl)-2-benzimidazolyl)-2-benzimidazolyl)-, trihydrochloride; p-(5-(4-Methyl-1-piperazinyl)(2,5'-bi-1H-benzimidazol)-2'-yl)phenol trihydrochloride; [ChemIDplus]

Category

Other Dyes

Description

Yellow-green powder; [Acros Organics MSDS]

Sources/Uses

"A benzimidazole antifilarial agent; it is fluorescent when it binds to certain nucleotides in DNA, thus providing a tool for the study of DNA replication; it also interferes with mitosis." [ChemIDplus]

Comments

Causes tearing, dyspnea, and salivary gland changes in intravenous lethal-dose studies of dogs; Causes convulsions, dyspnea, and death in 5-day intermittent intravenous studies of mice and rats; [RTECS] May cause irritation; [Acros Organics MSDS] See "BBOT." See "Bisbenzimide."

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