Agent Name

Olaquindox

CAS Number

23696-28-8

Formula

C12-H13-N3-O4

Major Category

Other Uses

Synonyms

2-(N-(2-Hydroxyethyl)karbamoyl)-3-methylchinoxalin-1,4-dioxid [Czech]; BAY Va 9391; Bayernox; Bayonox; Bisergon; N-(2-Hydroxyethyl)-3-methyl-2-quinoxalinecarboxamide 1,4-dioxide; Olachindox [Czech]; Olaquindoxum [INN-Latin]; 2-Quinoxalinecarboxamide, N-(2-hydroxyethyl)-3-methyl-, 1,4-dioxide; [ChemIDplus]

Category

Animal Feed Additives

Description

Pale yellow solid; [Merck Index] May cause irritation; Inhalation may cause sensitization, asthma symptoms, or breathing difficulties; Can cause photosensitivity; Harmful by ingestion; [Aldrich MSDS]

Sources/Uses

Used in animal feed as an antibiotic and growth promoter; [Kanerva, p. 1821]

Comments

Photocontact dermatitis reported in animal feed handlers; [Kanerva, p. 1821] Danger of photo-contact dermatitis; "Germ cell mutagens that have shown to increase the mutant frequency in the progeny of exposed mammals." [MAK] Causes weight loss, fatty liver degeneration, and renal tubule injury in 13-week intermittent oral studies of rats; [RTECS] Reports of photosensitive dermatitis in farm employees; [HSDB] May cause irritation; Inhalation may cause sensitization, asthma symptoms, or breathing difficulties; Can cause photosensitivity; Harmful by ingestion; [Aldrich MSDS]

Reference Link

Photoallergic contact dermatitis in a pig farmer caused by olaquindox

Exposure Assessment
Explanatory Notes

"Danger of photo-contact sensitization." [MAK]

Adverse Effects
Hepatotoxin

Hepatotoxin, Secondary

Dermatotoxin

Contact Dermatitis, Photoallergic

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Biomedical References

Search PubMed

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: