Agent Name

Tylosin

CAS Number

1401-69-0

Formula

C46-H77-N-O17

Major Category

Other Uses

Synonyms

(10E,12E)-(3R,4S,5S,6R,8R,14S,15R)-14-((6-deoxy-2,3-di-O-methyl-beta-D-allopyranosyl)oxymethyl)-5-((3,6-dideoxy-4-O-(2,6-dideoxy-3-C-methyl-alpha-L-ribo-hexopyranosyl)-3-dimethylamino-beta-D-glucopyranosyl)oxy)-6-formylmethyl-3-hydroxy-4,8,12-trimethyl-9-oxoheptadeca-10,12-dien-15-olide; (10E,12E)-(3R,4S,5S,6R,8R,14S,15R)-14-((6-deoxy-2,3-di-O-methyl-beta-D-allopyranosyl)oxymethyl)-5-((3,6-dideoxy-4-O-(2,6-dideoxy-3-C-methyl-alpha-l-ribo-hexopyranosyl)-3-dimethylamino-beta-d-glucopyranosyl)oxy)-6-formylmethyl-3-hydroxy-4,8,12-trimet; Fradizine; Tilosina [INN-Spanish]; Tylan; Tylocine; Tylosin A; Tylosin tartrate; Tylosine [INN-French]; Tylosinum [INN-Latin]; Vubityl 200; [ChemIDplus]

Category

Animal Feed Additives

Description

Solid; [Merck Index] White to buff-colored powder with a mild musty odor; [USP MSDS]

Sources/Uses

Tylosin is a veterinary macrolide antibiotic. [Kanerva, p. 1844] A macrolide antibiotic from a Streptomycetes fradiae strain found in the soil in Thailand; [Merck Index]

Comments

Occupational asthma has been reported; [Malo] Allergic contact dermatitis reported in farmers, feed mixers, and veterinarians; [Kanerva, p. 1844] An eye irritant; May cause contact dermatitis; May cause allergic reaction by inhalation, ingestion, or skin contact; Chronic exposure may cause hypersensitization; [USP MSDS]

Reference Link

Occupational asthma due to tylosin tartrate

Exposure Assessment
Vapor Pressure

1.98E-34 mm Hg

Reference Link

Occupational contact dermatitis from tylosin

Adverse Effects
Skin Sensitizer

Yes

Asthma

Yes

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

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Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: