Agent Name

Azathioprine

Alternative Name

Imuran

CAS Number

446-86-6

Formula

C9-H7-N7-O2-S

Major Category

Other Uses

Synonyms

Imuran; 1H-Purine, 6-((1-methyl-4-nitro-1H-imidazol-5-yl)thio)-; 6-((1-Methyl-4-nitro-1H-imidazol-5-yl)thio)-1H-purine; 6-((1-Methyl-4-nitroimidazol-5-yl)thio)purine; 6-(1'-Methyl-4'-nitro-5'-imidazolyl)-mercaptopurine; 6-(1-Methyl-4-nitroimidazol-5-ylthio)purin [Czech]; 6-(1-Methyl-p-nitro-5-imidazolyl)-thiopurine; 6-1'-Methyl,4'-nitro,5'-imidazolyl mercaptopurine; Azamun [Czech]; Azanin; Azasan; Azathioprin; Azathioprine; Azathioprinum [INN-Latin]; Azatioprin; Azatioprina [INN-Spanish]; BW 57-322; BW-57-322; Ccucol; Imurek; Imurel; Methylnitroimidazolylmercaptopurine; Muran; Purine, 6-(1-methyl-4-nitro-5-imidazolylthio)-; Rorasul; [ChemIDplus]

Category

Pharmaceuticals

Sources/Uses

Used as an immunosuppressant and anticancer drug; [Kanerva, p. 1753]

Comments

Allergic contact dermatitis reported in pharmaceutical workers (a packaging worker and a mechanic); [Kanerva, p. 1753]

Reference Link

Allergic contact dermatitis from azathioprine

Adverse Effects
Skin Sensitizer

Yes

IARC Carcinogen

Known Carcinogen

NTP Carcinogen

Human Carcinogen

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

Search ChemIDplus

Biomedical References

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: