Agent Name

Benzyl alcohol

CAS Number

100-51-6

Formula

C7-H8-O

Major Category

Other Classes

Synonyms

(Hydroxymethyl)benzene; Alcohol bencilico [INN-Spanish]; Alcoholum benzylicum [INN-Latin]; Alcool benzilico [DCIT]; Alcool benzylique; Alcool benzylique [INN-French]; Benzal alcohol; Benzenecarbinol; Benzenemethanol; Benzoyl alcohol; Benzyl alcohol; Benzyl alcohol (natural); Benzylicum; Euxyl K 100; Hydroxytoluene; Methanol, phenyl-; Phenolcarbinol; Phenylcarbinol; Phenylcarbinolum; Phenylmethanol; Phenylmethyl alcohol; alpha-Toluenol; [ChemIDplus]

Category

Alcohols and Polyols, Other

Description

A colorless liquid with a sharp burning taste and slight odor; [ChemIDplus]

Sources/Uses

Used as a preservative, epoxy resin catalyst, and in the photographic developer C-22; [Kanerva, p. 1757] Used as a preservative, solvent, and local anesthetic; [Marks, p. 136] Used as a preservative in drugs for injection; [Kanerva, p. 462-3] Used in flavors and perfumes and as a solvent for inks and dyes; [AIHA]

Comments

Rarely causes allergic contact dermatitis; [Marks, p. 136] Occupational contact urticaria has been reported. [PMID 11766131] A skin and eye irritant; Inhalation of high concentrations may cause CNS effects; May cause skin sensitization; [ICSC] No deaths in rats exposed to saturated concentrations (100-200 ppm) for 2 hours; Rapidly metabolized to hippuric acid; Has caused deaths in premature infants when given in IV solutions >4.5 mg/kg-day; [AIHA] Included in list of "established contact allergens in humans"; [ToxPlanet: EC: Scientific Committee on Consumer Safety: Fragrance allergens in cosmetic products (2011)]

Reference Link

Photographic allergens: an update

Exposure Assessment
MAK

5 ppm

WEEL

10 ppm

Vapor Pressure

0.09 mm Hg

Odor Threshold Low

5.5 ppm

Lethal Concentration

LCLo (rat) = 1,000 ppm/8h

Explanatory Notes

Flash point = 93 deg C; Odor threshold from CHEMINFO;

Reference Link

Occupational airborne allergic contact dermatitis in parquet layers

Adverse Effects
Skin Sensitizer

Yes

Neurotoxin

CNS Solvent Syndrome

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: