Agent Name

Benzyl alcohol

CAS Number

100-51-6

Formula

C7-H8-O

Major Category

Other Classes

Synonyms

(Hydroxymethyl)benzene; Alcohol bencilico [INN-Spanish]; Alcoholum benzylicum [INN-Latin]; Alcool benzilico [DCIT]; Alcool benzylique; Alcool benzylique [INN-French]; Benzal alcohol; Benzenecarbinol; Benzenemethanol; Benzoyl alcohol; Benzyl alcohol; Benzyl alcohol (natural); Benzylicum; Euxyl K 100; Hydroxytoluene; Methanol, phenyl-; Phenolcarbinol; Phenylcarbinol; Phenylcarbinolum; Phenylmethanol; Phenylmethyl alcohol; alpha-Toluenol; [ChemIDplus]

Category

Alcohols and Polyols, Other

Description

A colorless liquid with a sharp burning taste and slight odor; [ChemIDplus]

Sources/Uses

Used as a preservative, epoxy resin catalyst, and in the photographic developer C-22; [Kanerva, p. 1757] Used as a preservative, solvent, and local anesthetic; [Marks, p. 136] Used as a preservative in drugs for injection; [Kanerva, p. 462-3] Used in flavors and perfumes and as a solvent for inks and dyes; [AIHA]

Comments

Rarely causes allergic contact dermatitis; [Marks, p. 136] Occupational contact urticaria has been reported. [PMID 11766131] A skin and eye irritant; Inhalation of high concentrations may cause CNS effects; May cause skin sensitization; [ICSC] No deaths in rats exposed to saturated concentrations (100-200 ppm) for 2 hours; Rapidly metabolized to hippuric acid; Has caused deaths in premature infants when given in IV solutions >4.5 mg/kg-day; [AIHA] Included in list of "established contact allergens in humans"; [ToxPlanet: EC: Scientific Committee on Consumer Safety: Fragrance allergens in cosmetic products (2011)]

Reference Link

Photographic allergens: an update

Exposure Assessment
MAK

5 ppm

WEEL

10 ppm

Vapor Pressure

0.09 mm Hg

Odor Threshold Low

5.5 ppm

Lethal Concentration

LCLo (rat) = 1,000 ppm/8h

Explanatory Notes

Flash point = 93 deg C; Odor threshold from CHEMINFO;

Reference Link

Occupational airborne allergic contact dermatitis in parquet layers

Flammability (NFPA)

1: Must be preheated

Adverse Effects
Skin Sensitizer

Yes

Neurotoxin

CNS Solvent Syndrome

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

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Chemical Information

Search ChemIDplus

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: