Agent Name

Carbosulfan

CAS Number

55285-14-8

Formula

C20-H32-N2-O3-S

Major Category

Pesticides

Synonyms

Dibutylaminosulfenylcarbofuran; ((Dibutylamino)thio)methylcarbamic acid, 2,2-dimethyl-2,3-dihydro-7-benzofuranyl ester; 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate; 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl (di-n-butylaminosulfenyl)methylcarbamate; Advantage; FMC 35001; Marshal; Marshall; Posse; ((Dibutylamino)thio)methylcarbamic acid 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester; Carbamic acid, ((dibutylamino)thio)methyl-, 2,2-dimethyl-2,3-dihydro-7-benzofuranyl ester; Carbamic acid, ((dibutylamino)thio)methyl-, 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester; [ChemIDplus] MARSHAL 25CS; MARSHAL 10G; 2,3-Dihydro-2,2-dimethylbenzofuran-7-yl (dibutylaminothio)methylcarbamate; [ToxPlanet: EFSA: DAR - Vol. 1] UN2992

Category

Carbamate Insecticides

Description

Brown viscous liquid; [Merck Index] Medium yellow viscous liquid; Odorless to slight amine odor; [ToxPlanet: EFSA: DAR - Vol. 1]

Sources/Uses

No active pesticide product registrations in the US; [NPIRS] Used as an insecticide; [Merck Index] Approved in the EU for use on maize, sugarbeet, cotton, and citrus; [ToxPlanet: EFSA: DAR - Vol. 1]

Comments

Carbamate cholinesterase inhibitor; Hydrolyzed to carbofuran in the soil; [Merck Index] Insecticidal activity from the in vitro cleavage of the N-S bond forming carbofuran; Not irritating to skin or eyes; May cause skin sensitization; Developmental toxicity and teratogenicity observed in rats and rabbits at doses not overtly maternally toxic; No evidence of carcinogenicity or organophosphorus induced delayed neurotoxicity [ToxPlanet: EFSA: DAR - Vol. 1] A mild skin irritant; [RTECS] A mild skin irritant; May cause skin sensitization; Toxic by ingestion and inhalation; [Sigma-Aldrich MSDS] See "Carbofuran." See "CARBAMATE INSECTICIDES."

Exposure Assessment
BEI

Acetylcholinesterase activity in red blood cells = 70% of individual's baseline; Butylcholinesterase activity in serum or plasma = 60% of individual's baseline; Sample at end of shift; [TLVs and BEIs]

Vapor Pressure

3.07E-7 mm Hg

Lethal Concentration

LC50 (rat) = 1,530 mg/m3/1hr

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Carbamate pesticide, liquid, toxic."

Adverse Effects
Skin Sensitizer

Yes

Other Poison

Carbamate

Links to Other NLM Databases
Toxicity Information

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Chemical Information

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Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: