Agent Name

CHAPS

CAS Number

75621-03-3

Formula

C32-H58-N2-O7-S

Major Category

Other Uses

Synonyms

Cholamidopropyl)dimethylammonium)-1-propanesulfonate; 1-Propanaminium, N,N-dimethyl-3-sulfo-N-(3-(((3alpha,5beta,7alpha)-3,7,12-trihydroxy-24-oxocholan-24-yl)amino)propyl)-,hydroxide, inner salt; 3-((3-Cholamidopropyl)dimethylammonio)-1-propanesulfonate; 1-Propanaminium, N,N-dimethyl-N-(3-sulfopropyl)-3-(((3alpha,5beta,7alpha,12alpha)-3,7,12-trihydroxy-24-oxocholan-24-yl)amino)-, hydroxide, inner salt; [ChemIDplus] N,N-Dimethyl-N-(3-sulfopropyl)-3-[[(3alpha,5beta,7alpha,12alpha)-3,7,12-trihydroxy-24-oxocholan-24-yl]amino]-1-propanaminium inner salt; [Merck Index]

Category

Biochemical Research

Description

Solid; [Merck Index] White crystalline powder; [Amresco MSDS]

Sources/Uses

Used as a non-denaturing biological detergent; [Merck Index] "CHAPS is a zwitterionic detergent used in the laboratory to solubilize biological macromolecules such as proteins. It is used as a non-denaturing solvent in the process of protein purification and is especially useful in purifying membrane proteins, which are often sparingly soluble or insoluble in aqueous solution due to their native hydrophobicity." [Wikipedia]

Comments

A skin and strong eye irritant; [Amresco MSDS]

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