Ethylene glycol monobutyl ether; 2-Butoxy-1-ethanol; 2-Butoxyethanol; 3-Oxa-1-heptanol; BUCS; Butoxyethanol; Butyl cellosolve; Butyl cellu-sol; Butyl glycol; Butyl oxitol; Chimec NR; Dowanol EB; EGBE; EGMBE; Ektasolve EB; Ethanol, 2-butoxy-; Ethylene glycol butyl ether; Ethylene glycol n-butyl ether; Ethylene glycol, monobutyl ether; Gafcol EB; Glycol butyl ether; Glycol ether EB; Glycol monobutyl ether; Jeffersol EB; Monobutyl ether of ethylene glycol; Monobutyl ethylene glycol ether; O-Butyl ethylene glycol; Poly-Solv EB; n-Butoxyethanol; [ChemIDplus] UN2369
Glycol Ethers (E Series)
Colorless liquid with a mild, ether-like odor; [NIOSH]
Used as solvent in surface coatings; [ACGIH] Also used in hydraulic fluids, glass cleaners, and leather cleaners; [Sullivan, p. 1203] Used as a solvent in paints, coatings, inks, metal cleaners, and household cleaners; Occupational exposures are high in silk screen printing; [Reference #2]
Severe hemoglobinuria and changes in the lungs, kidneys, and liver are seen in mice after 7-hour lethal concentration studies. Volunteers showed no evidence of adverse effects other than mucous membrane irritation after 8 hour exposures to 200 ppm. No increase in red cell fragility was seen after these brief exposures. [ACGIH] For ethylene glycol ethers, there is limited positive evidence of spontaneous abortions and decreased sperm counts in humans and strong positive evidence of birth defects and testicular damage in animals. [ATSDR Case Studies # 29] Humans are resistant to butoxyethanol-induced red blood cell hemolysis. [Sullivan, p. 1204] See "Glycol ethers."
Butoxyacetic acid (BAA) in urine (with hydrolysis) = 200 mg/g creatinine at end of shift.
|Skin Designation (ACGIH)|
|Excerpts from Documentation for IDLHs|
Human data: It has been stated that humans would be able to tolerate saturated concentrations (i.e., about 1,000 ppm) for 1 hour without experiencing any significant nonreversible effects [Carpenter et al. 1956].
0.8 mm Hg
|Odor Threshold Low|
|Odor Threshold High|
LC50 (rat)= 450 ppm/4hr;
Detection odor threshold from AIHA (mean = 0.1 ppm); Flash point = 62 deg C;
0.6 to 4.8 hours [Sullivan, p. 1203]
CNS Solvent Syndrome
|Links to Other NLM Databases|
Human Health Effects from Hazardous Substances Data Bank:
|Related Information in HazMap|
Occupational diseases associated with exposure to this agent:
Industrial Processes with risk of exposure:
Activities with risk of exposure: