Agent Name

Clostridium botulinum neurotoxins

CAS Number

93384-43-1; 93384-44-2

Formula

Unspecified

Major Category

Biological Agents

Synonyms

BoNT-A; Botulinum Neurotoxin Type A; Botulinum neurotoxin; Clostridium botulinum neurotoxin A; Clostridium botulinum neurotoxin B; Clostridium botulinum neurotoxin C1; Clostridium botulinum neurotoxin D; Clostridium botulinum neurotoxin E; Clostridium botulinum neurotoxin F; Clostridium botulinum neurotoxin G; Neurotoxin, Clostridium botulinum; [ChemIDplus]

Category

Bacterial Toxins

Sources/Uses

Seven antigenically distinct neurotoxins produced by the spores of Clostridium botulinum; Types A, B, E, and F affect humans by interfering with the release of acetylcholine at peripheral nerve endings; [Merck Manual]

Comments

"Symptoms are symmetric cranial nerve palsies accompanied by a symmetric descending weakness and flaccid paralysis without sensory deficits." [Merck Manual] Causes ptosis and changes in extra-ocular muscles in acute intracerebral studies of mice; [RTECS]

Links to Other NLM Databases
Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Related Information in HazMap
Other Information

No other related information on this agent was found.