Agent Name

2-Butoxyethyl acetate

Alternative Name

EGBEA

CAS Number

112-07-2

Formula

C8-H16-O3

Major Category

Solvents

Synonyms

Ethylene glycol monobutyl ether acetate; 2-Butoxyethanol acetate; 2-Butoxyethyl acetate; Acetic acid, 2-butoxyethyl ester; Butoxyethyl acetate; Butyl cellosolve acetate; Butyl glycol acetate; EGBEA; Butylglycol acetate; Ektasolve EB acetate; Ethanol, 2-butoxy-, acetate; Ethylene glycol butyl ether acetate; Ethylene glycol monobutyl ether acetate; Glycol monobutyl ether acetate; n-Butoxyethanol acetate; [ChemIDplus]

Category

Glycol Ethers (E Series)

Description

Colorless liquid with a pleasant, sweet, fruity odor; [NIOSH]

Sources/Uses

Used as a solvent for lacquers, paints, enamels, resins, polymers, inks, and oils; [HSDB]

Comments

Rats and rabbits show kidney injury during 10 month inhalation toxicology studies. [HSDB] For ethylene glycol ethers, there is limited positive evidence of spontaneous abortions and decreased sperm counts in humans and strong positive evidence of birth defects and testicular damage in animals. [ATSDR Case Studies # 29] See "Glycol ethers."

Reference Link

ATSDR - ToxFAQs - 2-Butoxyethanol Acetate

Exposure Assessment
Skin Designation (ACGIH)

Insufficient data

TLV (ACGIH)

20 ppm

MAK

10 ppm, sum of the concentrations of EGBE and its acetate in air

Vapor Pressure

0.3 mm Hg

Odor Threshold Low

0.1 ppm

Odor Threshold High

0.48 ppm

Explanatory Notes

Flash point = 71 deg C; Odor threshold from CHEMINFO;

Reference Link

OECD SIDS: Monoethylene GlycoL Ethers - 2004

Adverse Effects
Neurotoxin

CNS Solvent Syndrome

Hepatotoxin

Hepatotoxin, Secondary

Nephrotoxin

Yes

Reproductive Toxin

Yes

ACGIH Carcinogen

Confirmed Animal

Links to Other NLM Databases
Health Studies

Human Health Effects from Hazardous Substances Data Bank:

Toxicity Information

Search TOXNET

Chemical Information

Search ChemIDplus

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: