Agent Name

Chymopapain

CAS Number

9001-09-6

Major Category

Biological Agents

Synonyms

BAX 1526; Chymodiactin; Chymopapaine [INN-French]; Chymopapainum [INN-Latin]; Discase; Quimopapaina [INN-Spanish]; [ChemIDplus]

Category

Enzymes

Description

Solid; [Merck Index]

Sources/Uses

Derived from papaya and used in meat tenderizers and to treat herniated lumbar discs (chemonucleolysis); [Merck Index]

Comments

Causes somnolence, convulsions, and respiratory depression in intravenous lethal-dose studies of mice and rats; [RTECS] A skin and strong eye irritant; May cause skin sensitization; Targets the CNS and kidney; [Sigma-Aldrich MSDS] See "ENZYMES."

Reference Link

Chemonucleolysis in lumbar disc herniation: a meta-analysis.

Adverse Effects
Skin Sensitizer

Yes

Links to Other NLM Databases
Toxicity Information

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Chemical Information

Search ChemIDplus

Related Information in HazMap
Diseases

Occupational diseases associated with exposure to this agent: